Curriculum Vitae
Curriculum Vitae
Work experience 👨🏭
- Analytical Scientist … 11/2023-present
- @ Hovione
- Scientist (Fractional Scholarship) … 09/2023-present
- Freelance Work & Innovation projects … 04/2023-present
- Medical content writer … 12/2022-04/2023
- @ freelance
- writting 1500-2000 word blog posts based on research published on PubMed, with a next-day delivery deadline.
- @ freelance
- PhD fellow … 03/2018-07/2022
- Junior researcher … 10/2017-03/2018
- @ 2Siglas DuasSiglas
- Portugal2020 founded project aiming to model the optimization of biological factors in ‘Rocha’ pear management in pre and post-harvest
- @ 2Siglas DuasSiglas
- Research fellow … 08/2017-10/2017
- @ Center of Eletronics, Optoelectronics and Telecommunication CEOT
- participation in the project: GoingOrganic/UID/Multi/00631/2013 CEOT
- @ Center of Eletronics, Optoelectronics and Telecommunication CEOT
- Junior researcher … 09/2016-05/2017
- @ 2Siglas DuasSiglas
- participation as lab/field researcher in four different EU founded projects (“IDT”)
- @ 2Siglas DuasSiglas
- Research fellow … 01/2016-08/2016
- @ Center of Eletronics, Optoelectronics and Telecommunication CEOT
- participation in the project: GoingOrganic/UID/Multi/00631/2013 CEOT
Education 🎓
- PhD Mechanisms of Disease and Regenerative Medicine … 03/2018-01/2023
- Universidade do Algarve/Universidade Nova de Lisboa
– PhD programme Mechanisms of Disease and Regenerative Medicine ProRegeM.
- Project title: From pluripotency to early events leading to cardiogenesis
- supervision: prof. José Bragança and prof. Rui Martinho
- Project title: From pluripotency to early events leading to cardiogenesis
- Universidade do Algarve/Universidade Nova de Lisboa
– PhD programme Mechanisms of Disease and Regenerative Medicine ProRegeM.
- MSc Biological engineering … 2009-2015
- Universidade do Algarve
- ERASMUS: University of Groningen for Master thesis … 02/2014 to 07/2014
- Dissertation title: Screening of process conditions for the production of biogas from diluted organic waste streams using microreactors
- supervision: prof. Gert-Jan Euverink and prof. Guilherme Ferreira
- Dissertation title: Screening of process conditions for the production of biogas from diluted organic waste streams using microreactors
- ERASMUS: University of Groningen for Master thesis … 02/2014 to 07/2014
- Universidade do Algarve
Training 🏫
- Summer School in Computational Biology … September 2023
- The Data Science Course 2023: Complete Data Science Bootcamp (Udemy:365datascience) … March 2023
- Fundamentals of Data Visualization in Tableau (Udemy:365datascience) … March 2023
- The Complete SQL Bootcamp 2022: Go from Zero to Hero (Udemy) … December 2022
- Introduction to digital bioimage analysis, 3rd edition (i3S, online) … October 2021
- Smart Microscopy (University of Gothenburg, online) … May 2021
- Flow Cytometry Workshop November (Universidade do Algarve) … November 2019
- “Introduction to LaTeX”(Universidade do Algarve) … September 2018
- VI cell culture and tissue training (Universidade de Coimbra) … July 2018
- R for absolute beginners 6th edition (Universidade do Algarve) … June 2018
Event participation 🏳
- Deloitte Tech Experience 2023 … 25:26/02/2023
- inCantanhede Innovation Days 2022 … 07/11/2022 & 11/11/2022
Awards 🏆
- FCT fellowship in the PhD programme ProRegeM … 2018
- ERASMUS fellowship … 2014
Languages 🌐
- Native language: Portuguese (C2)
- Second language: English (C1)
- Third language: French (A1)
Softwares and programming languages 💻
- Core:
- MS office suite (Word, Excel, PowerPoint), Visual Studio Code, Jupyter notebooks
- Documents:
- LaTex (TeXstudio)
- Programming:
- RStudio (R), Anaconda/Spyder (Python), MATLAB
- Data bases:
- Postgre SQL
- Statistics:
- SPSS
- Version control:
- GitHub (git)
- Engineering:
- SuperPro Designer
- Image processing:
- ImageJ, Cell Profiler, ImageLab, ZenBlue
- Data visualization:
- MS PowerBI, Tableau
- Project and Task management:
- Trello, Todoist, Notion, Toggl
- Image editing/vector graphics:
- Affinity Suite (Photo, Designer, Publisher)
- CaptureOne
- DxO Photololab
- On1
- Video/Audio editing:
- DaVinci Resolve
- Note taking:
- Obsidian, Evernote
Hobbies and other interests 🏃♂️
- Editing (text, image, video, sound)
- Photography and videography
- Scientific Illustration
- Sports: running, tennis and padel
Projects
- In silico tissue stratification
- a repository with the assigment from the training in computational biology summer school 2023 (see above)
- lab-meta-data
- a repository with template folders and json files to store experimental data and its respective metadata
- lab-excel-templates
- a repository with Excel templates for routine tasks in the laboratory (lifesciences)
- templates_thesis_UAlg
- a repository with MS Word templates for writing a dissertation/thesis following UAlg’s settings
Academic/Research 👨🔬
co-authored publications
biomedical
- Calado, S.M., Bento, D., Justino, D., Mendes-Silva, L., Marques, N. and Bragança, J., 2021. “Generation of a human induced pluripotent stem cell line (UALGi001-A) from a patient with Left-Ventricular Noncompaction Cardiomyopathy”. Stem Cell Research, 53, p.102302. link
- Fernandes, M.T., Calado, S.M., Mendes-Silva, L. and Bragança, J., 2020. CITED2 and the modulation of the hypoxic response in cancer. World Journal of Clinical Oncology, 11(5), p.260. link
- João M. A. Santos; Leonardo Mendes-Silva; Vanessa Afonso; Gil Martins; Rui S. R. Machado; João A. Lopes; Leonor Cancela; et al. “Exogenous WNT5A and WNT11 proteins rescue CITED2 dysfunction in mouse embryonic stem cells and zebrafish morphants”. Cell Death & Disease 10 8 (2019). link
- Bragança, J., Mendes-Silva, L., and Lopes, J.A.C., Sofia M. “CITED Proteins in the Heart of Pluripotent Cells and in Heart’s Full Potential”. Regenerative Medicine Frontiers (2019). link
- Bragança, José; Lopes, João André; Mendes-Silva, Leonardo; Santos, João Miguel Almeida. “Induced pluripotent stem cells, a giant leap for mankind therapeutic applications”. World Journal of Stem Cells 11 7 (2019): 421-430. link
- Tsunoda, S.; Avezov, E.; Zyryanova, A.; Konno, T.; Mendes-Silva, L.; Melo, E.P.; Harding, H.P.; Ron, D.. “Intact protein folding in the glutathione-depleted endoplasmic reticulum implicates alternative protein thiol reductants”. eLife 2014 3 (2014). link
postharvest biology
- Martins, J.A., Guerra, R., Pires, R., Antunes, M.D., Panagopoulos, T., Brázio, A., Afonso, A.M., Silva, L., Lucas, M.R. and Cavaco, A.M., 2022. “SpectraNet–53: A deep residual learning architecture for predicting soluble solids content with VIS–NIR spectroscopy”. Computers and Electronics in Agriculture, 197, p.106945. link
- Ana M. Cavaco, Sandra P. Cruz, M. Dulce Antunes, Rui Guerra, Rosa Pires, Andreia M. Afonso, António Brázio, Leonardo Silva, Márcia Rosendo Lucas, Mariana Daniel, Thomas Panagopoulos, “Spatiotemporal modelling of the quality and ripening of two cultivars of “Algarve Citrus” orchards at different edaphoclimatic conditions”, Postharvest Biology and Technology, Volume 172, 2021, 111386 link
- Cavaco, A.M., Pires, R., Antunes, M.D., Panagopoulos, T., Brázio, A., Afonso, A.M., Silva, L., Lucas, M.R., Cadeiras, B., Cruz, S.P., et al. (2018). “Validation of short wave near infrared calibration models for the quality and ripening of ‘Newhall’ orange on tree across years and orchards”. Postharvest Biol Technol 141, 86-97. link
not peer-reviweed
- Silva, L.; Cavaco, A. M.; Antunes, M. D.; Guerra, R. Effect of Orange Peel in Whole Oranges’ Spectra. Actas Portuguesas de Horticultura 2016, 28, 352–359.
Presentations
oral [1]
- Zebrafish as a model to study cited2-caused developmental defects
- @ 3ªs ABC meeting (28-29 March 2019, Albufeira, Portugal)
posters [3]
I am only considering the posters where I was the first author.
- Mendes-Silva, Leonardo, et al. “Zebrafish as model to study Cited2-caused developmental defects”.(2018) Secretome Without Borders, Braga, Portugal, Dez 2018.
- Leonardo Silva, Mafalda Sales-Gomes, Filipe Martins, Ana M. Cavaco, M. Dulce Antunes, Maria Leonor Faleiro (2017), “Case Study of shelf life of sweet-potato king’s cake”, 7th Congress of European Microbiologists, Valencia, Spain, July 9 – 13, 2017.
- Silva, L., Cavaco, A.M., Antunes, M.D., Guerra, R. (2016) “Effect of orange peel in whole oranges’ spectra”. IX Simpósio Ibérico de Maturação e Pós-Colheita. Lisboa, Portugal. 2-4 Nov 2016.
Mentoring
- 3 Bachelor student(s) … degree obtained: 3, ongoing: 0
- 1 MSc student(s) … degree obtained: 0, ongoing: 0
Faculty
- PhD program students representative … 2020-2023
- MSc students representative … 2012-2014
Science outreach
- Editor of the promotional video for the Stem Cells Day, available here
- Recording and edition of divulgation videos of experiments in the lab, available here
- Mendes-Silva, Leonardo; Bragança, José. Prevention of congenital heart anomalies: the secret kept by embryonic stem cells. 2021. Available here
- Mendes-Silva, Leonardo; Bragança, José “Os poderes secretos das células estaminais para limitar as malformações do coração”, UAlgoritmo, 2020, available here
- PhD project presentation at secodary school of Cantanhede in 2018
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by the author.